Skip to main content

Maropitant Citrate

Why has my veterinarian prescribed this medicine?

Your pet has been prescribed Cerenia (maropitant citrate) for the treatment of acute vomiting, and/or the prevention of vomiting associated with motion sickness in dogs. Use in cats is considered extra-label drug use (see below)

Adverse effects:

For the treatment of acute vomiting: Depression, ataxia, and trembling have been observed shortly after use of the product and generally resolve within 24 hours without treatment.

For the prevention of motion sickness: Because consumption of a small meal is required one hour before the administration of Cerenia, vomiting may occur within two hours post-dosing, and prior to travel. Some motion sickness dogs may show nausea-like signs during travel, including salivation and lethargy.

Other potential adverse reactions, listed in decreasing order:

  • Digestive tract disorders: vomiting, hypersalivation, diarrhea
  • Systemic disorders: lethargy, anorexia
  • Neurological disorders: muscle tremors, ataxia, sedation, convulsion

Storage and handling:

Store at a temperature between 15 and 30°C.

Topical exposure may elicit localized allergic skin reactions in some individuals. Repeated or prolonged exposure may lead to skin sensitization. In case of accidental skin exposure, wash with soap and water. In the case of accidental eye exposure, flush with water for 15 minutes and seek medical attention.

Please see the prescription label for dosing information and means of administration.

Always follow the label instructions. Never administer any medication unless prescribed by a veterinarian. Keep out of reach of children.

Zoetis Cerenia product monograph (package insert).

Extra-label drug use

Extra-label drug use, also referred to as “off-label use” refers to the use of a drug approved by Health Canada in an animal in a manner not in accordance with the label or package insert with respect to species, indication, dose, duration, and route of administration.

A drug used in an extra-label manner does not have proven safety or efficacy characteristic based on its intended use.

The availability of approved veterinary drugs for the species being treated is always considered before prescribing medication in an extra-label manner.

With the limited approved veterinary drugs, extra-label drug use often involves the use medications made for other species (including humans) in our pets.

© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Last updated on Nov 24, 2021.